BDBM50069582 (R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL96654

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1

InChI Key InChIKey=RZIOSGXPNNBJBD-RTWAWAEBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50069582   

TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)
Affinity DataIC50:  1.90E+3nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity of the compound towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069582((R)-N*1*-((S)-1-Benzylcarbamoyl-2-phenyl-ethyl)-N*...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed