BDBM50069642 5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL152685

SMILES CN(Cc1n[nH]c(=O)[nH]1)[C@H](COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=IEMQDTNVDLFVMI-QGZVFWFLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069642   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069642(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50:  0.430nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069642(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity for Tachykinin receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069642(5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity for Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed