BDBM50069657 2-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-acetamide::CHEMBL327765

SMILES CN(CC(N)=O)[C@H](COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=YVLZVIUUVUBKNC-QGZVFWFLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069657   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069657(2-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-ph...)
Affinity DataIC50:  5.80nMAssay Description:Affinity towards hNK1 receptor by displacement of [125I]- Substance P from hNK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50069657(2-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of binding to L-type [Ca2+] channelMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50069657(2-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-ph...)
Affinity DataIC50:  5.80nMAssay Description:Binding affinity to human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article