BDBM50070596 CHEMBL282549::N-Methyl-N-{3-[2-(pyridin-4-ylamino)-ethoxy]-phenyl}-benzenesulfonamide

SMILES CN(c1cccc(OCCNc2ccncc2)c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=QNSIKAKIUZRPEO-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070596   

TargetProthrombin(Homo sapiens (Human))
Thrombosis Research Institute

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi:  63nMAssay Description:Binding affinity towards human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Thrombosis Research Institute

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi:  70nMAssay Description:Compound was tested in vitro for its ability to inhibit serine protease thrombin using succinyl-Ala-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Thrombosis Research Institute

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi:  70nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50070596(CHEMBL282549 | N-Methyl-N-{3-[2-(pyridin-4-ylamino...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of bovine trypsin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article