BDBM50070632 4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-pyridinium::CHEMBL23813::N-{3-[2-(Pyridin-4-ylamino)-ethoxy]-phenyl}-benzenesulfonamide

SMILES O=S(=O)(Nc1cccc(OCCNc2ccncc2)c1)c1ccccc1

InChI Key InChIKey=QHNMEYRLLYBYGG-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50070632   

TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  23nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  300nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi:  316nMAssay Description:Binding affinity towards human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of bovine trypsin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlasminogen(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070632(4-[2-(3-Benzenesulfonylamino-phenoxy)-ethylamino]-...)
Affinity DataKi: >5.00E+5nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human plasmin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
In DepthDetails Article