BDBM50072212 2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-quinazolin-7-yloxy]-ethanol::CHEMBL318444

SMILES CCc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2ccc(OCCO)cc2n1

InChI Key InChIKey=HJNIZRXKOPEASX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072212   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)
Affinity DataIC50:  630nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)
Affinity DataIC50:  850nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)
Affinity DataIC50:  660nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed