BDBM50072375 4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide::CHEMBL57486::L-757793

SMILES CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1

InChI Key InChIKey=RKIRUNUDHJGEGW-MHZLTWQESA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50072375   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cAMP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Beta-2 adrenergic receptor binding affinity in CHO cells expressing cloned human receptor in the presence of 125 I-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataEC50:  6.30nMAssay Description:Agonism against Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataEC50:  6.30nMAssay Description:Tested in vitro for its ability to stimulate increase in cAMP in CHO cellsexpressing the cloned human beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataIC50:  8.00E+3nMAssay Description:Beta-1 adrenergic receptor binding affinity in CHO cells expressing cloned human receptor in the presence of 125 I-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cAMP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataEC50:  6.30nMAssay Description:In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]-iodocyanopindolol as radioligand to stimulate increase in cA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50072375(4-(3-Hexyl-ureido)-N-{4-[2-((R)-2-hydroxy-2-pyridi...)
Affinity DataEC50:  6.30nMAssay Description:Binding affinity of the compound towards human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed