BDBM50072700 2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::CHEMBL67362

SMILES CC1=CC(C)(C)Nc2ccc-3c(COc4ccccc-34)c12

InChI Key InChIKey=CNWLUDPVYBPOSX-UHFFFAOYSA-N

Data  3 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072700   

TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50072700(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50072700(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen...)
Affinity DataKi:  84nMAssay Description:Inhibition of human progesterone receptor activation in T47D human breast cancer cell.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Scientific Computing

Curated by ChEMBL
LigandPNGBDBM50072700(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysen...)
Affinity DataKi:  84nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed