BDBM50073444 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one::CHEMBL621::TRAZODONE

SMILES Clc1cccc(c1)N1CCN(CCCn2nc3ccccn3c2=O)CC1

InChI Key InChIKey=PHLBKPHSAVXXEF-UHFFFAOYSA-N

Data  43 KI  12 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50073444   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  42nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  96nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  320nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  1.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi:  3.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50073444(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}[1,2...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed