BDBM50074720 6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::6-(2,5-dimethoxybenzyl)-5,6,7,8-tetrahydroquinazoline-2,4-diamine::CHEMBL7375

SMILES COc1ccc(OC)c(CC2CCc3nc(N)nc(N)c3C2)c1

InChI Key InChIKey=YGCBRLOKQASAIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074720   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  34nMAssay Description:The ability of the compound to inhibit rat liver Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  21nMAssay Description:The ability of the compound to inhibit T. gondii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50074720(6-(2,5-Dimethoxy-benzyl)-5,6,7,8-tetrahydro-quinaz...)
Affinity DataIC50:  57nMAssay Description:The ability of the compound to inhibit P. carinii Dihydrofolate reductase was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed