BDBM50074916 [(R)-2,2-Dimethyl-1-({(S)-naphthalen-2-yl-[3,3,3-trifluoro-1-(4-guanidino-benzyl)-2-oxo-propylcarbamoyl]-methyl}-carbamoyl)-propyl]-carbamic acid adamantan-1-yl ester

SMILES CC(C)(C)[C@@H](NC(=O)OC12CC3CC(CC(C3)C1)C2)C(=O)N[C@H](C(=O)NC(Cc1ccc(NC(N)=[NH2+])cc1)C(=O)C(F)(F)F)c1ccc2ccccc2c1

InChI Key InChIKey=FSQMPBMPAVBLCK-RQEWZCSHSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074916   

TargetPlasminogen(Rattus norvegicus)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074916([(R)-2,2-Dimethyl-1-({(S)-naphthalen-2-yl-[3,3,3-t...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074916([(R)-2,2-Dimethyl-1-({(S)-naphthalen-2-yl-[3,3,3-t...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity of compound against human plasma Kallikrein (PK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074916([(R)-2,2-Dimethyl-1-({(S)-naphthalen-2-yl-[3,3,3-t...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibitory activity of compound against Tissue Kallikrein (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed