BDBM50074921 [(R)-1-({(S)-Naphthalen-2-yl-[3,3,3-trifluoro-1-(4-guanidino-benzyl)-2-oxo-propylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](C(=O)NC(Cc1ccc(NC(N)=[NH2+])cc1)C(=O)C(F)(F)F)c1ccc2ccccc2c1

InChI Key InChIKey=NGYXFSALIODLKO-ZECMKTFBSA-O

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074921   

TargetPlasminogen(Rattus norvegicus)
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074921([(R)-1-({(S)-Naphthalen-2-yl-[3,3,3-trifluoro-1-(4...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity of compound against Plasmin (HP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074921([(R)-1-({(S)-Naphthalen-2-yl-[3,3,3-trifluoro-1-(4...)
Affinity DataKi:  89nMAssay Description:Inhibitory activity of compound against human plasma Kallikrein (PK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
The Procter & Gamble

Curated by ChEMBL
LigandPNGBDBM50074921([(R)-1-({(S)-Naphthalen-2-yl-[3,3,3-trifluoro-1-(4...)
Affinity DataKi:  2.23E+5nMAssay Description:Inhibitory activity of compound against Tissue Kallikrein (TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed