BDBM50075214 CHEMBL3414876

SMILES Cc1ccc(cc1)S([O-])(=O)=O.ON1C(=O)Cc2cc(Cc3ccc(cc3)-c3cc[nH+]cc3)ccc2C1=O

InChI Key InChIKey=AIULDGIMEZNMLG-UHFFFAOYSA-O

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50075214   

TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Moloney murine leukemia virus reverse transcriptase polymerase activity using Td100/Pd18 DNA-DNA substrate incubated for 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of HIV integrase pre-incubated for 10 mins before DNA substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  500nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in internal cleavage using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by li...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in DNA 3' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  800nMAssay Description:Inhibition of reconstituted HIV1 RNase H using RNA/DNA duplex substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075214(CHEMBL3414876)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase associated catalytically active RNase H domain assessed as reduction in RNA 5' end directed clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed