BDBM50075474 CHEMBL3415352

SMILES COc1cc(cc(OC)c1OC)-c1nc(SCC#C)nc(NNC(N)=S)c1C#N

InChI Key InChIKey=QSJWHWXROPOHCT-UHFFFAOYSA-N

Data  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50075474   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to recombinant LSD1(unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: >1.25E+6nMAssay Description:Inhibition of MAOB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50: >1.25E+6nMAssay Description:Inhibition of MAOA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50:  650nMAssay Description:Inhibition of recombinant LSD1 (157 to 852) (unknown origin) transfected in Escherichia coli BL21(DE) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50:  650nMAssay Description:Inhibition of LSD1 (unknown origin) (157 to 852 residues) expressed in Escherichia coli BL21(DE) cells using H3K4me2 as substrate by horseradish pero...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50:  650nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50:  650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50:  650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50075474(CHEMBL3415352)
Affinity DataIC50:  650nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed