BDBM50075624 6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethylamino]phenyl}-6-(3-pyridyl)-(E)-5-hexenoic acid::6-{3-[1-(tert-butylamino)-2-cyano-(Z)-1-iminomethylamino]phenyl}-6-(3-pyridyl)-(Z)-5-hexenoic acid::CHEMBL281398::CHEMBL7718

SMILES CC(C)(C)NC(Nc1cccc(c1)C(=CCCCC(O)=O)c1cccnc1)=NC#N

InChI Key InChIKey=XUTLOCQNGLJNSA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50075624   

TargetThromboxane A2 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075624(6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...)
Affinity DataIC50:  11nMAssay Description:In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075624(6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...)
Affinity DataIC50:  4nMAssay Description:In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075624(6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro activity on thromboxane A2 receptor antagonism in gel filtered human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075624(6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory concentration of compound against thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075624(6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro activity on thromboxane A2 synthase inhibition in gel filtered human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50075624(6-{3-[1-(tert-butylamino)-2-cyano-(E)-1-iminomethy...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory concentration of compound against thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed