BDBM50075842 (S)-2-({5-[2-((E)-4-Chloro-pyridin-3-yl)-vinyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid::CHEMBL433519

SMILES CSCC[C@H](NC(=O)c1ccc(\C=C\c2cnccc2Cl)cc1-c1ccccc1C)C(O)=O

InChI Key InChIKey=CHVJSILONSNEQT-UMESLIDUSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075842   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50075842((S)-2-({5-[2-((E)-4-Chloro-pyridin-3-yl)-vinyl]-2'...)Copy SMILESCopy InChI

Affinity DataIC50:  0.290nMAssay Description:Inhibitory activity against farnesyltransferase (FT) using SPA assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI