BDBM50076049 3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL100941

SMILES COC(=O)C1C2CCC(C2)CC1c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=FAWYJKWTZBQTRU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076049   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)
Affinity DataIC50:  33.4nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)
Affinity DataIC50:  33nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter (SERT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Macaca fascicularis)
Organix

Curated by ChEMBL
LigandPNGBDBM50076049(3-(3,4-Dichloro-phenyl)-bicyclo[3.2.1]octane-2-car...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed