BDBM50076706 (7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one::CHEMBL266269

SMILES CC[C@@H]1Cc2cc3c(cc(=O)[nH]c3cc2N[C@@H]1C)C(F)(F)F

InChI Key InChIKey=WDRIFNRAGUVDQZ-RKDXNWHRSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076706   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076706((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Affinity DataKi:  15nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076706((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076706((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Affinity DataEC50:  10nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed