BDBM50076708 (6S,8R)-6,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one::CHEMBL7383

SMILES CC[C@@H]1C[C@H](CC)c2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F

InChI Key InChIKey=WPOYIISPHKTSEM-VHSXEESVSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076708   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076708((6S,8R)-6,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human androgen receptor (hAR), using dihydrotestosterone as radioligand for competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076708((6S,8R)-6,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cells; no dataMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076708((6S,8R)-6,8-Diethyl-4-trifluoromethyl-6,7,8,9-tetr...)
Affinity DataEC50:  32nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed