BDBM50077401 (R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid hydroxyamide::CHEMBL291757

SMILES ONC(=O)[C@H]1Cc2c(CN1S(=O)(=O)c1ccc(Oc3ccccc3)cc1)[nH]c1ccccc21

InChI Key InChIKey=OREVCDGKIGJEIW-HSZRJFAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077401   

TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077401((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077401((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human neutrophil collagenase, Matrix Metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077401((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed