BDBM50078390 (S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl)-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-ethyl)-amide::CHEMBL309274

SMILES CC(C)C[C@H](N)[C@H](O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(N)=O

InChI Key InChIKey=PDGQBIYMLALKTR-BJDJZHNGSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50078390   

TargetXaa-Pro dipeptidase(Homo sapiens (Human))
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition against Prolidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 2(Rattus norvegicus)
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Activity against membrane bound rat aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 2(Homo sapiens (Human))
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition against membrane bound human aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50:  4.50E+5nMAssay Description:Inhibition against Leucyl aminopeptidase from pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 2(Homo sapiens (Human))
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition against membrane bound monkey aminopeptidase PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 1(Homo sapiens (Human))
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition against cytosolic Aminopeptidase P from human heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 1(Homo sapiens (Human))
Pharmacia And Upjohn

Curated by ChEMBL
LigandPNGBDBM50078390((S)-1-((2S,3S)-3-Amino-2-hydroxy-5-methyl-hexanoyl...)
Affinity DataIC50: >8.00E+5nMAssay Description:Inhibition against Aminopeptidase P from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed