BDBM50078566 (S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-butyramide::CHEMBL296911

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@@H](CCSCc1ccccc1)C(=O)NO

InChI Key InChIKey=TWQZYQBXMVVVCY-NRFANRHFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078566   

TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  104nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed