BDBM50080448 3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane::CHEMBL119013

SMILES CN1C2CCC1CC(C2)OC(c1ccccc1)c1cccc(Cl)c1

InChI Key InChIKey=FMPUWHUXNOPVQS-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50080448   

TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50080448(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...)
Affinity DataKi:  0.980nMAssay Description:Binding affinity for muscarinic m1 receptor was determined in vitro in rat brain using [3H]pirenzepine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50080448(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...)
Affinity DataKi:  21.6nMAssay Description:Binding affinity for dopamine transporter was determined in vitro in rat brain using [3H]WIN-35428 s radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50080448(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]WIN-35428 binding to the dopamine transporter in rat caudate putamen tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50080448(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...)
Affinity DataKi:  258nMAssay Description:Binding affinity for serotonin transporter was determined in vitro in rat brain using [3H]citalopram as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50080448(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...)
Affinity DataKi:  451nMAssay Description:Binding affinity for norepinephrine transporter in rat brain using [3H]-nisoxatine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50080448(3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...)
Affinity DataIC50:  228nMAssay Description:Inhibition of [3H]dopamine uptake in rat caudate putamen tissue.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed