BDBM50081589 CHEMBL101399::N*4*,N*4*-Dibenzyl-6-phenyl-pteridine-2,4-diamine

SMILES Nc1nc(N(Cc2ccccc2)Cc2ccccc2)c2nc(cnc2n1)-c1ccccc1

InChI Key InChIKey=QSNZOWTXIXJCER-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081589   

TargetNitric oxide synthase, endothelial(Sus scrofa)
Julius-Maximilians University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50081589(CHEMBL101399 | N*4*,N*4*-Dibenzyl-6-phenyl-pteridi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against Nitric oxide synthase (derived from porcine brain cerebellum)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50081589(CHEMBL101399 | N*4*,N*4*-Dibenzyl-6-phenyl-pteridi...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50081589(CHEMBL101399 | N*4*,N*4*-Dibenzyl-6-phenyl-pteridi...)
Affinity DataIC50:  1.29E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50081589(CHEMBL101399 | N*4*,N*4*-Dibenzyl-6-phenyl-pteridi...)
Affinity DataIC50:  4.52E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50081589(CHEMBL101399 | N*4*,N*4*-Dibenzyl-6-phenyl-pteridi...)
Affinity DataIC50:  3.43E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed