BDBM50081626 CHEMBL336318::N-(2-{4-[Ethyl-(3-isobutyl-pyridin-2-yl)-amino]-piperidine-1-carbonyl}-1H-indol-5-yl)-methanesulfonamide

SMILES CCN(C1CCN(CC1)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2[nH]1)c1ncccc1CC(C)C

InChI Key InChIKey=GSMFRJRLFKAMMB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081626   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081626(CHEMBL336318 | N-(2-{4-[Ethyl-(3-isobutyl-pyridin-...)
Affinity DataIC50:  880nMAssay Description:Inhibition of Reverse transcriptase (Y181C) using poly(rA)600:oligo(dT)10 as template primer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081626(CHEMBL336318 | N-(2-{4-[Ethyl-(3-isobutyl-pyridin-...)
Affinity DataIC50:  430nMAssay Description:Inhibition of Reverse transcriptase (P236L) using poly(rA)600:oligo(dT)10 as template primer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50081626(CHEMBL336318 | N-(2-{4-[Ethyl-(3-isobutyl-pyridin-...)
Affinity DataIC50:  410nMAssay Description:Inhibition of Reverse transcriptase (Wild Type) with poly(rA)600:oligo(dT)10 template primerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed