BDBM50081867 (2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-methylethan-2-ylsulfonamido)methyl)-4-oxo-4-(piperidin-1-yl)butanamide::(2R,3R)-3-Cyclopentylmethyl-2-[(ethanesulfonyl-methyl-amino)-methyl]-N-hydroxy-4-oxo-4-piperidin-1-yl-butyramide::CHEMBL99148

SMILES CCS(=O)(=O)N(C)C[C@@H]([C@@H](CC1CCCC1)C(=O)N1CCCCC1)C(=O)NO

InChI Key InChIKey=ZVAKMIZOMSWYGQ-SJORKVTESA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50081867   

TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Strom-1 MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Gel-A MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  603nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  398nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081867((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed