BDBM50082019 2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1,2-dihydro-quinolin-7-yl]-acetamide::CHEMBL137509

SMILES Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(NC(=O)CCl)ccc12

InChI Key InChIKey=IRBFMKXALXRYAJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082019   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Université

Curated by ChEMBL
LigandPNGBDBM50082019(2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1...)
Affinity DataKi:  278nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50082019(2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1...)
Affinity DataIC50:  3.80E+4nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed