BDBM50082022 2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinolin-3-yl)-phenylamino]-ethanesulfonyl fluoride::CHEMBL337346

SMILES Oc1c(-c2cccc(NCCS(F)(=O)=O)c2)c(=O)[nH]c2cc(Cl)ccc12

InChI Key InChIKey=PWSNMZQMCLBAOZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082022   

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Université

Curated by ChEMBL
LigandPNGBDBM50082022(2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinoli...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Université

Curated by ChEMBL
LigandPNGBDBM50082022(2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50:  335nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed