BDBM50083760 CHEMBL86991::[3-Oxo-8-[3-(pyridin-2-ylamino)-propoxy]-2-(2,2,2-trifluoro-ethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl]-acetic acid

SMILES OC(=O)C[C@H]1Cc2ccc(OCCCNc3ccccn3)cc2CN(CC(F)(F)F)C1=O

InChI Key InChIKey=PVDGZHKJXXVONO-MRXNPFEDSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083760   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083760(CHEMBL86991 | [3-Oxo-8-[3-(pyridin-2-ylamino)-prop...)
Affinity DataKi:  20nMAssay Description:Binding affinity for Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083760(CHEMBL86991 | [3-Oxo-8-[3-(pyridin-2-ylamino)-prop...)
Affinity DataIC50:  390nMAssay Description:HEK cell adhesion mediated by alpha v beta 3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed