BDBM50084207 (R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL346442

SMILES CC(C)(C)O\N=C1\C[C@@H](N(C1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO

InChI Key InChIKey=YBRVBUDXSMPLGQ-YPFLROGLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084207   

TargetCollagenase 3(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50084207((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenox...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibition of human recombinant collagenase-3 (Matrix metalloproteinase-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50084207((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenox...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloproteinase-1, MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50084207((R)-4-[(Z)-tert-Butoxyimino]-1-[4-(4-fluoro-phenox...)
Affinity DataIC50:  1.03E+3nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloproteinase-7, MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed