BDBM50085255 2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl}-oxazole::CHEMBL117132

SMILES C(CN1CCCC1)Oc1ccc(Oc2ccc(cc2)-c2ncco2)cc1

InChI Key InChIKey=IMGGKNXDSXRLHK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085255   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085255(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human leukotriene A4 hydrolase (LTA-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085255(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085255(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human whole blood LTB-4 production (Leukotriene B-4).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085255(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085255(2-{4-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenoxy]-phenyl...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed