BDBM50085283 1-[2-(4-Benzyl-phenoxy)-ethyl]-azepane::CHEMBL159263

SMILES C(CN1CCCCCC1)Oc1ccc(Cc2ccccc2)cc1

InChI Key InChIKey=XMEYRISTYAMHBD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085283   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50085283(1-[2-(4-Benzyl-phenoxy)-ethyl]-azepane | CHEMBL159...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity was determined against Leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50085283(1-[2-(4-Benzyl-phenoxy)-ethyl]-azepane | CHEMBL159...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity was determined for LTB4 production in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Bio-Science And Technology

Curated by ChEMBL
LigandPNGBDBM50085283(1-[2-(4-Benzyl-phenoxy)-ethyl]-azepane | CHEMBL159...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute Of Bio-Science And Technology

Curated by ChEMBL
LigandPNGBDBM50085283(1-[2-(4-Benzyl-phenoxy)-ethyl]-azepane | CHEMBL159...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute Of Bio-Science And Technology

Curated by ChEMBL
LigandPNGBDBM50085283(1-[2-(4-Benzyl-phenoxy)-ethyl]-azepane | CHEMBL159...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed