BDBM50085414 3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid methyl ester::CHEMBL424048

SMILES COC(=O)c1ccc2NC(=O)\C(=C/c3cc(Br)c(O)c(Br)c3)c2c1

InChI Key InChIKey=XGIIRMLBZISRPR-WCIBSUBMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085414   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085414(3-[1-(3,5-Dibromo-4-hydroxy-phenyl)-meth-(Z)-ylide...)
Affinity DataIC50:  13nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed