BDBM50085416 5-(2-Chloro-acetyl)-3-[1-(3,5-dibromo-4-hydroxy-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL72179

SMILES Oc1c(Br)cc(C=C2C(=O)Nc3ccc(cc23)C(=O)CCl)cc1Br

InChI Key InChIKey=FMYPBTOEYTUDMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085416   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50085416(5-(2-Chloro-acetyl)-3-[1-(3,5-dibromo-4-hydroxy-ph...)
Affinity DataIC50:  65nMAssay Description:Inhibition of cRaf1 kinase in cascade assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed