BDBM50085554 5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5')ADENOSINE::CHEMBL414948::Oligoadenylate analogue

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]3n3cnc4c(N)ncnc34)O[C@H]2n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O

InChI Key InChIKey=SIIZPVYVXNXXQG-UQTMIEBXSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085554   

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataEC50:  0.200nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataIC50:  7.30nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085554(5'-O-MONOPHOSPHORYLADENYLYL(2'->5')ADENYLYL(2'->5'...)
Affinity DataEC50:  0.150nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB