BDBM50088873 2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indol-6-yl)-1-ethanamine::CHEMBL172159

SMILES NCCc1cn2CCSc3cc(Cl)cc1c23

InChI Key InChIKey=YGRCBGOVANCRBN-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088873   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity of the compound towards human 5-hydroxytryptamine 2C receptor expressed in HEK-293 cells was determined using [3H]-mesulerg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataKi:  631nMAssay Description:In vitro binding affinity of the compound towards human 5-hydroxytryptamine 2A receptor expressed in HEK-293 cells was determined using [3H]-ketanser...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataEC50:  0.230nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intra-cellular calcium mobilization for 5-HT2c receptor ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataEC50:  348nMAssay Description:In vitro binding affinity of the compound towards human 5-hydroxytryptamine 2C receptor expressed in HEK-293 cells was determined using [3H]-mesulerg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed