BDBM50088978 CHEMBL176515::N-[1-(1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-ethyl]-3-hydroxy-2-phenylmethanesulfonylamino-propionamide

SMILES C[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)Cc1ccccc1)C(=O)N[C@H]1CCCN(C1O)C(N)=N

InChI Key InChIKey=JYLDIRMFPPDHNN-YBVBUHPZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088978   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50088978(CHEMBL176515 | N-[1-(1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  5.10nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50088978(CHEMBL176515 | N-[1-(1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  275nMAssay Description:The compound was tested in vitro for its inhibitory activity against human Plasmin enzyme, activity expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50088978(CHEMBL176515 | N-[1-(1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:The compound was tested in vitro for its inhibitory activity against human t-PA enzyme, activity expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed