BDBM50089716 4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-(3-methoxy-benzyl)-5-phenyl-2H-pyrazole-3-carboxylic acid::CHEMBL26474

SMILES COc1cccc(Cn2nc(c(Cc3cc4OCOc4cc3Cl)c2C(O)=O)-c2ccccc2)c1

InChI Key InChIKey=FGOULBWWTIMGSP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50089716   

TargetEndothelin receptor type B(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089716(4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-(3-meth...)
Affinity DataIC50:  34nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089716(4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-(3-meth...)
Affinity DataIC50:  18nMAssay Description:In vitro binding affinity to endothelin A receptor in rat heart ventriclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089716(4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-(3-meth...)
Affinity DataIC50:  34nMAssay Description:In vitro binding affinity to endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089716(4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-(3-meth...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed