BDBM50089724 4-Benzo[1,3]dioxol-5-ylmethyl-2-(2-chloro-benzyl)-5-trifluoromethyl-2H-pyrazol-3-ol::CHEMBL3144600

SMILES FC(F)(F)c1[nH]n(Cc2ccccc2Cl)c(=O)c1Cc1ccc2OCOc2c1

InChI Key InChIKey=ZKHNDJXOHIXYTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089724   

TargetEndothelin-1 receptor(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089724(4-Benzo[1,3]dioxol-5-ylmethyl-2-(2-chloro-benzyl)-...)
Affinity DataIC50:  3.80E+3nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089724(4-Benzo[1,3]dioxol-5-ylmethyl-2-(2-chloro-benzyl)-...)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed