BDBM50089727 2,4-Bis-benzo[1,3]dioxol-5-ylmethyl-5-trifluoromethyl-2H-pyrazol-3-ol::CHEMBL3144602

SMILES FC(F)(F)c1[nH]n(Cc2ccc3OCOc3c2)c(=O)c1Cc1ccc2OCOc2c1

InChI Key InChIKey=GSYUSCVEJUNUJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50089727   

TargetEndothelin receptor type B(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089727(2,4-Bis-benzo[1,3]dioxol-5-ylmethyl-5-trifluoromet...)
Affinity DataIC50:  1.70E+4nMAssay Description:In vitro inhibition of [125-I] labelled ET-1 endothelin binding to Endothelin B receptor in rat cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50089727(2,4-Bis-benzo[1,3]dioxol-5-ylmethyl-5-trifluoromet...)
Affinity DataIC50:  5.60E+3nMAssay Description:In vitro inhibition of endothelin binding to endothelin A receptor in rat heart ventricles was measured using a 125-I labelled ET-1 competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed