BDBM50090148 4-[2-((R)-4-Fluoro-3-fluoro-phenyl)-oxazol-4-yl]-N-{4-[2-(2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide::CHEMBL40898

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2coc(n2)-c2ccc(F)c(F)c2)cc1)c1cccnc1

InChI Key InChIKey=DNCQXUOWEHOOQR-LJAQVGFWSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090148   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090148(4-[2-((R)-4-Fluoro-3-fluoro-phenyl)-oxazol-4-yl]-N...)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro binding affinity at beta-2 adrenergic receptors in the presence of [125]iodocyanopindolol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090148(4-[2-((R)-4-Fluoro-3-fluoro-phenyl)-oxazol-4-yl]-N...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro binding affinity at beta-1 adrenergic receptors in the presence of [125]iodocyanopindolol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090148(4-[2-((R)-4-Fluoro-3-fluoro-phenyl)-oxazol-4-yl]-N...)
Affinity DataEC50:  35nMAssay Description:In vitro efficacy at beta-3 adrenoceptors, quantified by measuring intracellular cAMP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed