BDBM50090151 CHEMBL290053::N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-benzenesulfonamide

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2coc(n2)-c2ccc(cc2)C(F)(F)F)cc1)c1cccnc1

InChI Key InChIKey=XLXGQVQLOQQNPQ-LJAQVGFWSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090151   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090151(CHEMBL290053 | N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro binding affinity at beta-2 adrenergic receptors in the presence of [125]iodocyanopindolol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090151(CHEMBL290053 | N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro binding affinity at beta-1 adrenergic receptors in the presence of [125]iodocyanopindolol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090151(CHEMBL290053 | N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-...)
Affinity DataEC50:  22nMAssay Description:In vitro efficacy at beta-3 adrenoceptors, quantified by measuring intracellular cAMP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed