BDBM50090169 CHEMBL39577::N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(2-pentyl-oxazol-5-yl)-benzenesulfonamide

SMILES CCCCCc1ncc(o1)-c1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)c2cccnc2)cc1

InChI Key InChIKey=WENQKJQTJBPMGQ-MHZLTWQESA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50090169   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090169(CHEMBL39577 | N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro binding affinity at beta-2 adrenergic receptors in the presence of [125]iodocyanopindolol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090169(CHEMBL39577 | N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  26nMAssay Description:In vitro efficacy at beta-3 adrenoceptors, quantified by measuring intracellular cAMP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50090169(CHEMBL39577 | N-{(R)-4-[2-(2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  200nMAssay Description:In vitro binding affinity at beta-1 adrenergic receptors in the presence of [125]iodocyanopindolol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed