BDBM50090327 (R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide::CHEMBL288768

SMILES CC1=C([C@H](CC(=O)N1)c1ccc(F)c(F)c1)C(=O)NCCCN1CCC(CC1)(C#N)c1ccc(F)cc1

InChI Key InChIKey=WLHRCQLHMHKOKG-JOCHJYFZSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090327   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090327((R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6...)
Affinity DataKi:  1.80nMAssay Description:In vitro antagonism at Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090327((R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6...)
Affinity DataKi:  63nMAssay Description:Selectivity screen against human Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090327((R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6...)
Affinity DataKi:  1.04E+3nMAssay Description:In vitro antagonism at Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50090327((R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6...)
Affinity DataKi:  1.05E+3nMAssay Description:In vitro antagonism at Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed