BDBM50090593 2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-yl]-N-[2-(3-methyl-3H-imidazol-4-yl)-ethyl]-acetamide::CHEMBL48236

SMILES Cn1cncc1CCNC(=O)CN1CCN(CC1=O)S(=O)(=O)c1cc2ccc(Cl)cc2s1

InChI Key InChIKey=VDMOSQMSSHIXRC-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50090593   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  12nMAssay Description:Inhibition of Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  12nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >2.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >4.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >7.30E+3nMAssay Description:Compound was evaluated for the inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >8.70E+3nMAssay Description:Compound was evaluated for the inhibitory activity against t-PA.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.80E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed