BDBM50090757 (R)-3-Isopropylamino-chroman-5-carboxylic acid amide::CHEMBL319403

SMILES CC(C)NC1COc2cccc(C(N)=O)c2C1

InChI Key InChIKey=FVAVMEQKDWJQEM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090757   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi:  397nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]-SCH-23,390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]-raclopride from D2A receptor expressed in mouse ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed