BDBM50090968 CHEMBL3582035

SMILES Cn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)c4nnn(c4C(F)(F)F)-c4ccccc4)cc3F)c2s1

InChI Key InChIKey=AEXYDYPBGQQOMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090968   

TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090968(CHEMBL3582035)
Affinity DataIC50:  17nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090968(CHEMBL3582035)
Affinity DataIC50:  670nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed