BDBM50092339 CHEMBL3581648::US9675697, RX-7

SMILES COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccncc21

InChI Key InChIKey=NCPRCNJIGPDNGS-UHFFFAOYSA-N

Data  10 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092339   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50092339(CHEMBL3581648 | US9675697, RX-7)
Affinity DataKi:  824nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50092339(CHEMBL3581648 | US9675697, RX-7)
Affinity DataKi:  1.64E+3nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50092339(CHEMBL3581648 | US9675697, RX-7)
Affinity DataIC50:  2.69E+3nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD2 (333 to 460 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50092339(CHEMBL3581648 | US9675697, RX-7)
Affinity DataIC50:  4.59E+3nMAssay Description:Displacement of FAM-labeled ZBA248 from BRD4 BD1 (44 to 168 amino acid residues) (unknown origin) expressed in Rosetta2 DE3 cells after 30 mins by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed