BDBM50096142 CHEMBL3593985

SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O

InChI Key InChIKey=DTXVXYKICRFJQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096142   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Malaya

Curated by ChEMBL
LigandPNGBDBM50096142(CHEMBL3593985)
Affinity DataIC50:  460nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly (ADP-ribose) onto histone protein after 60 mins by TACS-Sapphire...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50096142(CHEMBL3593985)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of DHODH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50096142(CHEMBL3593985)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of DHODH (unknown origin) using L-DHO, DUQ, DCIP as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed