BDBM50097695 CHEMBL3590191

SMILES CC(C)N(CCNC(=O)c1ccc2CN(CCc2c1)S(=O)(=O)c1ccc(C)cc1)Cc1ccc(F)cc1

InChI Key InChIKey=AROJNSXAIBTZKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097695   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50:  29nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50:  478nMAssay Description:Antagonist activity against human kappa opioid receptor expressed in human U2OS cells co-expressing beta-arrestin2 pre-treated for 15 mins before U69...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50097695(CHEMBL3590191)
Affinity DataIC50:  406nMAssay Description:Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cells assessed as inhibition of U69,593-induced ERK ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed